Taxonomy: f. Hexamitidae
Animal: Giardia intestinalis (research) 02 12.jpg
Sites: N/A
Nitroimidazole reduction in Giardia intestinalis. (Peter Boreham's colleagues in his lab at QIMR, Peter and Jacqui Upcroft, investigated the biochemistry and genetics of Giardia intestinalis to further understand the molecular mechanisms of drug resistance) Note: PFOR is a key component in metabolism of nitroimidazoles. activity of PFOR inversely correlated in vitro with drug sensitivities of different isolates (more detailed information- see Ellis et al 1993. IJP; 23:35-39; Townson, Boreham, Upcroft and Upcroft 1994. Acta Tropica;54:173-194 and other papers by these authors)

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